Coccidioides meningitis

Definition

Meningitis occurs in one-third to one-half of those with disseminated coccidioidomycosis. It frequently occurs as the only manifestation of disseminated disease. The presentation is headache with decreased mental acuity. The CSF profile displays a lymphocytic pleocytosis with elevated protein and reduced glucose concentrations. Coccidioidal serologic tests for IgG are usually positive but Coccidioides is infrequently cultured from CSF.

Inclusions

• Coccidioidomycosis meningitis

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