2A52

Myeloid or lymphoid neoplasms with FGFR1 abnormalities

Neoplasias mieloides ou linfoides com anormalidades de FGFR1

Category

Definition

Hematologic neoplasms characterised by the rearrangement of the FGFR1 gene, resulting in translocations with an 8p11 breakpoint. Patients may present with a myeloproliferative neoplasm, acute myeloid leukaemia, lymphoblastic lymphoma/leukaemia of T or B-cell lineage, or acute leukaemia of mixed phenotype.

Index Terms

Myeloid or lymphoid neoplasms with FGFR1 abnormalities