3A50.4

Hereditary persistence of fetal haemoglobin

Persistência hereditária de hemoglobina fetal

Category

Definition

Hereditary persistence of fetal haemoglobin (HPFH) associated with beta-thalassaemia is a haemoglobinopathy characterised by high haemoglobin (Hb)F levels and an increased number of fetal-Hb-containing cells. The association of HPFH with beta-thalassaemia mitigates the clinical manifestations which vary from a normal state to beta-thalassaemia intermedia.

Index Terms

Hereditary persistence of fetal haemoglobinHPFH - [Hereditary persistence of fetal haemoglobin]fetal haemoglobinpersistence of fetal haemoglobinpersistent haemoglobin FHereditary persistence of fetal haemoglobin, deletionalHereditary persistence of fetal haemoglobin, non-deletional