3B65

Thrombotic microangiopathy, not elsewhere classified

Microangiopatia trombótica, não classificada em outra parte.

Category

Definition

Thrombotic microangiopathies are microvascular occlusive disorders characterised by systemic or intrarenal aggregation of platelets, thrombocytopenia, and mechanical injury to erythrocytes. Thrombotic thrombocytopenic purpura (TTP) and haemolytic–uremic syndrome (HUS) represent a spectrum of thrombotic microangiopathies. In TTP, systemic microvascular aggregation of platelets causes ischemia in the brain and other organs. In HUS, platelet–fibrin thrombi predominantly occlude the renal circulation.

Index Terms

Thrombotic microangiopathy, not elsewhere classifiedAcute intravascular thrombotic microangiopathyAcute intravascular thrombi microangiopathyChronic intravascular thrombotic microangiopathyChronic intravascular thrombi microangiopathy