Volatile inhalant-induced mood disorder

Essential (Required) Features:

• The presentation is characterized by mood symptoms (e.g., depressed or elevated mood, decreased engagement in pleasurable activities, increased or decreased energy levels) that develop during or soon after intoxication with or withdrawal from volatile inhalants.
• The intensity or duration of the mood symptoms is substantially in excess of mood symptoms that are characteristic of Volatile Inhalant Intoxication or Volatile Inhalant Withdrawal.
• The symptoms are not better accounted for by another mental disorder such as a Depressive Disorder, a Bipolar Disorder, or Schizophrenia or Other Primary Psychotic Disorder. Evidence supporting a diagnosis of another mental disorder would include mood symptoms preceding the onset of volatile inhalant use, the symptoms persisting for a substantial period of time after cessation of volatile inhalant use or withdrawal (e.g., 1 month or more), or other evidence of a pre-existing mental disorder with mood symptoms (e.g., a history of prior episodes not associated with volatile inhalant use).
• The symptoms are not a manifestation of another medical condition.
• The symptoms cause significant distress or significant impairment in personal, family, social, educational, occupational or other important areas of functioning.

When making a diagnosis of Volatile Inhalant-Induced Mood Disorder, an additional diagnosis indicating the related pattern of volatile inhalant use should also be assigned. These include Episode of Harmful Use of Volatile Inhalants, Harmful Pattern of Use of Volatile Inhalants, and Volatile Inhalant Dependence. A diagnosis of Volatile Inhalant Intoxication or Volatile Inhalant Withdrawal may also be assigned if applicable.

Specifiers for volatile inhalant-induced mood symptoms:

An additional specifier can be added to denote the presence of either depressive symptoms in the absence of manic symptoms, manic symptoms in the absence of depressive symptoms, or mixed manic and depressive symptoms.

6C4B.700 Volatile Inhalant-Induced Mood Disorder with depressive symptoms

• All diagnostic requirements for Volatile Inhalant-Induced Mood Disorder are met.
• The presentation is characterized by depressive symptoms judged to be the direct consequence of the use of or withdrawal from a specified substance or medication.
• Manic symptoms are not present.

6C4B.701 Volatile Inhalant-Induced Mood Disorder with manic symptoms

• All diagnostic requirements for Volatile Inhalant -Induced Mood Disorder are met.
• The presentation is characterized by manic symptoms judged to be the direct consequence of the use of or withdrawal from a specified substance or medication.
• Depressive symptoms are not present.

6C4B.702 Volatile Inhalant-Induced Mood Disorder with mixed depressive and manic symptoms

• All diagnostic requirements for Volatile Inhalant -Induced Mood Disorder are met.
• The presentation is characterized by both depressive and manic symptoms judged to be the direct consequence of the use of or withdrawal from a specified substance or medication.

6C4B.70Z Volatile Inhalant-Induced Mood Disorder, unspecified

Additional Clinical Features:

• Volatile Inhalant-Induced Mood Disorder may present with patterns of symptoms that vary according to the characteristics of the user (e.g., genetics, metabolism, personality factors). Volatile Inhalants use in higher amounts or over longer periods of time is more likely to be associated with the development of a Volatile Inhalant-Induced Mood Disorder.
• Symptoms of Volatile Inhalant-Induced Mood Disorder usually resolve or improve after sustained cessation of volatile inhalant use.
• The duration of Substance Withdrawal for some substances can be protracted. For substances with more protracted withdrawal periods, the onset of symptoms of Substance-Induced Mood Disorder can occur up to several weeks after the cessation of substance use. Substance-Induced Mood Disorder symptoms related to substances with more protracted withdrawal periods may also last for correspondingly longer periods of time.
• In cases in which multiple psychoactive substance are used, it is often challenging to distinguish which substance is the cause of the Substance-Induced Mood Disorder. When the specific etiological substance cannot be determined, a diagnosis of Substance-Induced Mood Disorder Due to Multiple Specified Psychoactive Substances including Medications may assigned. In cases of multiple psychoactive substance use in which more than one specific substance can be identified as a cause of the Substance-Induced Mood Disorder, the corresponding specific Substance-Induced Mood Disorder diagnoses should be given instead.

Boundary with Normality (Threshold):

• Symptoms of Volatile Inhalant-Induced Mood Disorders should be differentiated from transient physiological aftereffects of intoxication (‘hangover effect’). The duration or severity of the symptoms in Volatile Inhalant-Induced Mood Disorders must be in excess of ‘hangover effects’ of Volatile Inhalants and result in significant distress or impairment of functioning.

Boundaries with Other Disorders and Conditions (Differential Diagnosis):

• Boundary with Volatile Inhalant Intoxication and Volatile Inhalant Withdrawal: Mental or behavioural symptoms that occur during Volatile Inhalant Intoxication or Volatile Inhalant Withdrawal should only be used as a basis for diagnosing a Volatile Inhalant-Induced Mood Disorder if the intensity or duration of the symptoms is substantially in excess of those that are characteristic of Volatile Inhalant Intoxication or Volatile Inhalant Withdrawal and the symptoms are sufficiently severe to warrant specific clinical attention.
• Boundary with Episode of Harmful Use of Volatile Inhalants, Harmful Pattern of Use of Volatile Inhalants, or Volatile Inhalant Dependence: The impact of repeated or continuous use of volatile inhalants characteristic of Harmful Pattern of Use of Volatile Inhalants and Volatile Inhalants Dependence may include Volatile Inhalant-Induced Mood Disorder. Volatile Inhalant-Induced Mood Disorders can also be associated with a single episode of volatile inhalant use. In such cases, a Volatile Inhalant-Induced Mood Disorder should be diagnosed together with a primary diagnosis of Episode of Harmful Use of Volatile Inhalants, Harmful Pattern of Use of Volatile Inhalants, or Volatile Inhalant Dependence.
• Boundary with mental disorders not induced by volatile inhalants: Volatile Inhalant-Induced Mood Disorders are differentiated from mental disorders with similar features that are not induced by volatile inhalants on the basis of their onset, course and clinical features. A diagnosis of Volatile Inhalant-Induced Mood Disorder requires evidence from history, physical or mental examination, or laboratory findings of recent volatile inhalant use, intoxication or withdrawal. Most Volatile Inhalant-Induced Mental Disorders resolve or improve within several weeks of cessation of volatile inhalant use. Mental disorders not induced by volatile inhalants may precede the onset of volatile inhalant use or may continue to be symptomatic during periods of sustained abstinence. The co-occurrence of volatile inhalant use or withdrawal and onset of symptoms of mental disorders should not be taken as evidence for a presumptive diagnosis of a Volatile Inhalant-Induced Mood Disorder. Some people use substances to suppress symptoms of mental disorders (e.g., Schizophrenia and Other Primary Psychotic Disorders, Mood Disorders, Anxiety and Fear-Related Disorders, Personality Disorders) and full symptomatic presentations only emerge upon cessation or reduction in substance use. Furthermore, volatile inhalant use can exacerbate symptoms or precipitate an episode of a pre-existing mental disorder. Finally, volatile inhalant use may be associated with but not aetiologic for new onset of symptoms of a mental disorder. Although a diagnosis of a Volatile Inhalant-Induced Mood Disorder should not be assigned under these circumstances, an additional diagnosis of Episode of Harmful Use of Volatile Inhalants, Harmful Pattern of Use of Volatile Inhalants, or Volatile Inhalant Dependence may still be appropriate.