6D85.8
Dementia due to pellagra
Demência devido à pelagra
CategoryDefinition
Dementia due to pellagra is caused by persistent lack of vitamin B3 (niacin) or tryptophan either in the diet or due to poor absorption in the gastrointestinal tract due to disease (e.g., Crohn disease) or due to the effects of some medications (e.g., isoniazid). Core signs of pellagra include dermatological changes (sensitivity to sunlight, lesions, alopecia, and oedema) and diarrhoea. With prolonged nutritional deficiency cognitive symptoms that include aggressivity, motor disturbances (ataxia and restlessness), confusion, and weakness are observed. Treatment with nutritional supplementation (e.g., niacin) typically results in reversal of symptoms.
Diagnostic Criteria
- All diagnostic requirements for Dementia are met.
- Dementia is presumed to be attributable to Pellagra, as demonstrated by neuropsychological test data, medical tests, and/or clinical history.
- Dementia Due to Pellagra is caused by persistent lack of vitamin B3 (niacin) or tryptophan either in the diet or due to poor absorption in the gastrointestinal tract due to disease (e.g., Crohn disease) or due to the effects of some medications (e.g., isoniazid).
- Core signs of Pellagra include dermatological changes (sensitivity to sunlight, lesions, alopecia, and edema) and diarrhea.
- With prolonged nutritional deficiency neurocognitive symptoms that include aggression, motor disturbances (ataxia and restlessness), confusion, and weakness may be observed.
- Treatment with nutritional supplementation (e.g., niacin) typically results in reversal of symptoms.
Note: A diagnosis of 5B5C.0 Pellagra should also be assigned.
Index Terms
Dementia due to pellagraDementia due to niacin deficiency