7A42.0

Obesity hypoventilation syndrome

Síndrome obesidade-hipoventilação

Category

Definition

Obesity hypoventilation syndrome is characterised by obesity (in adults, Body-Mass-Index > 30 kg/m²) and daytime hypercapnia indicated by arterial partial pressure of carbon dioxide (PaCO2) > 45 mm Hg that cannot be fully attributed to an underlying cardiopulmonary or neurologic disease. Hypercapnia worsens during sleep and is often associated with severe arterial oxygen desaturation. Obstructive sleep apnoea is also present in the majority of cases and should be diagnosed in addition to obesity hypoventilation. Note: A definitive diagnosis requires demonstration of daytime hypercapnia and objective evidence based on polysomnography, with carbon dioxide (CO2) monitoring (by arterial, end-tidal or transcutaneous measures).

Inclusions

  • Pickwickian syndrome

Index Terms

Obesity hypoventilation syndromePickwickian syndromecardiopulmonary obesity syndromeExtreme obesity with alveolar hypoventilation with Body-Mass-Index unspecifiedalveolar hypoventilation syndromealveolus hypoventilation syndromeOHS - [obesity hypoventilation syndrome]Obesity hypoventilation syndrome with BMI 30.00-34.99Obesity with alveolar hypoventilation with Body-Mass-Index of 30 but less than 35Obesity hypoventilation syndrome with BMI 35.00-39.99Obesity with alveolar hypoventilation with Body-Mass-Index of 35 but less than 40Obesity hypoventilation syndrome with BMI greater than or equal to 40.00Extreme obesity with alveolar hypoventilation with Body-Mass-Index of 40 and more