8A00.10
Progressive supranuclear palsy
Paralisia supranuclear progressiva
CategoryDefinition
Progressive supranuclear palsy (PSP) is a late-onset neurodegenerative disease characterised by supranuclear gaze palsy, postural instability, progressive rigidity, and mild dementia. Five clinical variants have been described with clinicopathological correlations: Classical PSP (Richardson's syndrome), and four atypical variants of PSP including PSP-Parkinsonism (PSP-P), PSP-Pure akinesia with gait freezing (PSP-PAGF), PSP-corticobasal syndrome (PSP-CBS), and PSP-progressive non fluent aphasia (PSP-PNFA).
Index Terms
Progressive supranuclear palsySteele-Richardson-Olszewksi syndromeAtypical progressive supranuclear palsyProgressive supranuclear palsy - corticobasal syndromeProgressive supranuclear palsy - parkinsonismProgressive supranuclear palsy - progressive non fluent aphasiaProgressive supranuclear palsy - pure akinesia with gait freezingClassical progressive supranuclear palsy