DB95.0

Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis

Doença hepática tóxica ou induzida por droga com necrose hepática aguda ou hepatite aguda

Category

Definition

This is an acute hepatocellular injury that develops within 1 to 20 weeks after starting treatment. The histological lesions consist mainly of focal, zonal or bridging necrosis, but lobular and portal tract inflammation evident with drug hepatitis. Extrahepatic features of drug hypersensitivity, including rash, lymphadenopathy, eosinophilia or other systemic features, are observed in some cases.

Index Terms

Drug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitisDrug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis, with complicationsDrug-induced or toxic liver disease with acute hepatic necrosis or acute hepatitis, without complications