Acute haemorrhagic oedema of infancy

Definition

Acute haemorrhagic oedema is an immune complex-mediated cutaneous vasculitis usually associated with respiratory infection or immunization. It affects children between the ages of 4 months and 2 years, with males being affected twice as frequently as females. The dramatic clinical appearance of facial and limb oedema with multiple targetoid purpuric macules belies its generally benign course.

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