GA30.6
Premature ovarian failure
Falência ovariana prematura
CategoryDefinition
Menopause occurring spontaneously before 40 years of age, generally resulting in secondary amenorrhea although some women may exhibit intermittent ovarian function and ovulation, with a minority conceiving and delivering a pregnancy. POF/POI occurs mostly without a known cause, but can be caused by the following conditions: numerical and structural chromosomal abnormalities, Fragile X (FMR1) premutations, autoimmune disorders, radiation therapy, chemotherapy, galactosemia, and other rare enzyme defects or mutations. To be subdivided in 4 categories according to cause: congenital, acquired, iatrogenic and unknown
Exclusions
- Isolated gonadotropin deficiency
- Postprocedural ovarian failure
Index Terms
Premature ovarian failurefemale hypergonadotropic hypogonadismhypergonadotrophic ovarian failureprimary female hypogonadismPOF - [premature ovarian failure]premature ovarian insufficiencyprimary ovarian insufficiencyovarian failureovarian secretion suppressionovary hyposecretionovary secretion deficiencypremature menopause NOSAcquired premature ovarian failureIatrogenic premature ovarian failurePremature ovarian failure of unknown originprimary ovarian failure NOSCongenital Premature ovarian failureDecreased oestrogenFemale hypogonadism syndromeovarian hypogonadismHypofunction of ovaryInsufficiency of ovary