GB81
Autosomal dominant polycystic kidney disease
Doença renal policística autossômica dominante
CategoryDefinition
Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and due to mutations on chromosomes 16 and 4. Non-renal manifestations can include cysts in the liver and less commonly pancreas. Cerebral arterial aneurysms with subarachnoid haemorrhage, and other non-renal vascular abnormalities can also occur.
Index Terms
Autosomal dominant polycystic kidney diseaseadult polycystic kidney diseasePolycystic kidney, adult typeAPCKD - [autosomal polycystic kidney disease]Autosomal dominant polycystic kidney disease type 1 without tuberous sclerosisADPCKD1 - [autosomal dominant polycystic kidney disease type 1]APCKD1 - [autosomal polycystic kidney disease type 1]Autosomal dominant polycystic kidney disease, Type 2ADPCKD2 - [autosomal dominant polycystic kidney disease type 2]APCKD2 - [autosomal polycystic kidney disease type 2]PKD2 gene - [polycystic kidney disease type 2 gene]