Constitutional delay of growth and puberty

Definition

Delayed development concerning maturation of bones and their growth at prepubertal and pubertal ages of children. Occurs with or without short stature below the third percentile of body height. Height velocity is usually temporarily below the mean. Bone age is always delayed. Puberty starts late, but spontaneously. Other causes of delayed growth (with or without short stature below the third percentile of body height) or of delayed puberty must be excluded.

Exclusions

• Short stature, not elsewhere classified
• Short stature due to growth hormone resistance

Index Terms