3A51
Sickle cell disorders or other haemoglobinopathies
Doenças falciformes e outras hemoglobinopatias
CategoryDefinition
Any disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may present with fatigue, shortness of breath, dizziness, headaches, pallor of skin or mucous membranes, and jaundice. This disorder is confirmed by identification of HbS mutation by genetic testing.
Subcategories (12)
3A51.0Sickle cell trait3A51.1Sickle cell disease without crisis3A51.2Sickle cell disease with crisis3A51.3Compound heterozygous sickling disorders without crisis3A51.4Compound heterozygous sickling disorders with crisis3A51.5Haemoglobin C disease3A51.6Haemoglobin D disease3A51.7High affinity haemoglobin3A51.8Low affinity haemoglobin3A51.9Haemoglobin O disease3A51.AHaemoglobin E disease3A51.BHaemoglobin C/beta thalassaemia compound heterozygosity